https://help.mikrotik.com/docs/display/ROS/MikroTik+wired+interface+compatibility
Question:
One of our partners are planning a new project for their end customer. They plan to use Cisco core switches (C9500-48Y4C-A with SFP-10G-SR=) and MikroTik (CRS328-4C-20S-4S+RM with S+85DLC03D) like an aggregation switch to which other ToR 1GbE MikroTik switches will be connected. The end customer's application servers will connect to the 1GbE MikroTik switches like the drawing below.
The partner is requesting a confirmation that their planned topology of using MikroTik with their Cisco Core switch will work fine and that there will not be any incompatibility by combining two different products in their network.
Answer:
MikroTik devices and SFP, SFP+, SFP28, QSFP+, and QSFP28 modules do not have any restrictions for other vendor equipment.
While MikroTik cannot ensure full compatibility with modules from all manufacturers, but as long as the other vendor modules and devices comply with transceiver multi-source agreement (MSA) they should be compatible with MikroTik.
More information on Mikrotik module compatibility is here:
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